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In this lecture we discuss reverse transcriptase, an enzyme that produces DNA from RNA.
What is a Virus?In this lecture we discuss reverse transcriptase, an enzyme that produces DNA from RNA.
What is a Virus?In this lecture we discuss the mechanisms for assembly of new virus particles.
The Infectious CycleViral reproduction places enormous demands on the host cell's biosynthetic and metabolic capabilities.
Genomes and GeneticsThis course now moves to a discussion of viral pathogenesis, the process by which viruses cause disease.
Structure of VirusesHost barriers against virus infections, which include chemical and physical defenses such as skin and mucus.
Attachment and EntryThe final barrier to virus reproduction in the host is the adaptive immune system, which is tailored to the pathogen and has memory
RNA directed RNA synthesisA process called pathogenesis - through a combination of the effects of virus replication and the immune response.
Transcription and RNAAn acute infection is characterized by rapid onset of virus reproduction, a brief but potentially severe course of disease.
Viral DNA ReplicationA persistent viral infection typically lasts for the lifetime of the host. In this lecture we discuss the mechanisms and consequences.
Reverse transcriptionAbout 20% of human cancers are associated with virus infections. Making cells immortal places them on the road to cancer.
AssemblyIn this lecture we discuss examples of how different types of vaccines work, including inactivated vaccines, subunit vaccines.
The Infected CellUnlike most vaccines, antiviral drugs can stop an infection once it has started. In this lecture we discuss antiviral drug discovery.
Infection Basics